Paper
Zinc Status among Type (2) Diabetes Mellitus in the State of Qatar
- Authors:
- Mohamad Daghash; Ibrahim Mohammad; Buthaina Alowainati; Lubna Mahmood; Amin Jaiosi; Ghazi Daradkeh; Mahmoud Zerie; Mohamad Othman; Prem Chandra
- Abstract
- To assess the serum zinc level in Type (2) diabetic patients and their association with both blood glucose level and lipid profile. Methods: The collection of data was carried out during the period from Jan 2007 to Nov 2007 in outpatient diabetic clinic at Hamad General Hospital, state of Qatar. 315 Type (2) diabetic patients (aged 25 65) who were previously diagnosed and attended diabetic clinics were selected by systematic random sampling technique. Anthropometric measurements (weight, height, and BMI) of the patients were recorded and venous blood samples drawn from each subject following an overnight fasting for 12 hours, in tube containing 0.15 % EDTA. Blood samples for Zinc determination were collected in Zinc free polypropylene tubes and the separated serum was stored at -20 o C until being analyzed. Zinc determination was performed in duplicate with an atomic absorption method by using flame atomic absorption. All lab tests were done in the central laboratory at Hamad Medical Corporation. RESULTS: The 315 subjects included, 148 (47 %) males and 167 (53 %) females 25-65 years old with a mean age of 50.04 ± 8.46. 172 (54.6 %). 116 (36.8 %) were overweight and obese and 27 (8.6 %) were with a normal body weight, with a mean body mass index of (29.25 ± 3.50), 214 (67.9 %) had uncontrolled blood sugar of HbA1C >7.5%. 51 (16.9 %) had hypercholesterolemia and 102 (23.4 %) had hypertriglyceridemia. 60 (19%) subjects were zinc-deficient (Zn < 70 µg), and 41 (68.3 %) of them had uncontrolled blood sugar of HbA1c>7.5%. 11(18.3 %) had hypercholesterolemia, and17(28.3 %) had hypertriglyceridemia, 38 (73.1 %) and 6 (10.0 %) of the zinc-deficient patients were with low HDL-c and high LDL-c levels, respectively. CONCLUSIONS: The results showed that zinc deficiency is common among type 2 diabetic patients due to hyperglycemia and polyurea. Periodic serum zinc measurement is recommended for type 2 diabetes mellitus.
- Keywords
- Zinc; Diabetes Mellitus; EDTA; HbA1C; BMI
- StartPage
- 4
- EndPage
- 10
- Doi
- 10.5963/PHF0301002