Paper
Chemistry behind the Elastic Nature of the Biomaterial Prepared Using Oxidized Form of Glutaraldehyde and Chitosan - An Approach at 2D and 3D Level
- Authors:
- Sailakshmi G.; Tapas Mitra; Suvro Chatterjee; A. Gnanamani
- Abstract
- This is the time to search an alternative cross-linker which will provide a non-toxic and mechanically stable biopolymer material. In order to achieve the requisite property, in the present study, we have chosen glutaric acid and studied its interaction with chitosan. A 3D scaffold biopolymer material prepared using chitosan and glutaric acid, displayed requisite mechanical strength and in addition found biocompatible for NIH 3T3 fibroblast cells. The interaction chemistry and the characteristics of the biopolymer material obtained upon cross-linking suggest non-covalent interactions play the major role in deciding the property of the said materials and its suitability for biomedical applications.
- Keywords
- Ionic Cross-Linking; Glutaric Acid; Glutaraldehyde; Chitosan; Bioinformatics
- StartPage
- 64
- EndPage
- 75
- Doi
- 10.5963/LSMR0302004