Paper
Comprehensive Solvent System for Counter -Current Chromatographic Separation of Natural Antioxidant Flavonoids from Traditional Chinese Medicines
- Authors:
- Shihua Wu; Dingfang Wu
- Abstract
- Flavonoids are a group of ubiquitous polyphenolic plant metabolites and found to be one of major active principles of some Traditional Chinese Medicines (TCMs). There is an increasing interest on the separation and identification of flavonoids with biological activities, such as antioxidant, antitumor, and inhibition of a variety enzyme. Recently, counter-current chromatography (CCC), a unique support-free liquid-liquid partition chromatography, has been widely used to isolate and purify bioactive natural products such as flavonoids from various plants especially from TCMs. As well known, the successful CCC separation largely depends on the selection of two-phase solvent system for the target compound(s). Therefore, the present summarizes two-phase solvent systems recently used in separation of a variety of bioactive flavonoids especially from TCMs. It is very important for current natural product isolation and TCMs research and development.
- Keywords
- Counter-Current Chromatography; Flavonoids; Natural Products; Phenolics; Solvent Systems; Traditional Chinese Medicines
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- EndPage
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