Blood Lead Levels and Bio-markers of Lead Toxicity via the Consumption of Drinking Water in Kerou (Benin) in Watershed of the Niger

Bernadin ELEGBEDE; Patrick A. EDORH; Alain K. AISSI; Luc KOUMOLOU; Koffi KOUDOVO; Sabine MONTCHO; Michel BOKO; Patient GUEDENON; Christophe KAKI
This survey made an assessment of bio markers witnesses of a chronic poisoning to the lead via the consumption of the drinking water whose contamination has been proved in the cotton zone of Kérou. Contents of lead measured out in samples of water of boreholes and out in blood plasma by atomic absorption spectrophotometer have been compared. To check the health impact of water pollution by pesticides and toxic metals, the present study conducted the collection of blood and urine of 39 residents, following the ethical rules. Kerou in Benin is a good reference of a site to test the hypothesis of the connection between water pollution with heavy metals (Pb in the present investigation) and human health and the intensity of farming activities and cotton cultivation in the zone. After laboratory analyses, the calculation of the Daily Exposure Dose (DED) showed high doses of toxic substances especially the lead in the plasma. These high values can be attributed to residues of pesticides. Results also show a lead level in blood interrelation in water for boreholes F3, F5 and F7. The blood lead limit has been passed in zones of the F12 boreholes, F16 and F18. Signs of poisoning to the lead are not marked at the level of the biochemical parameters but at the level of symptoms of lead poisoning have been observed within the investigated population of the residents. These results were confirmed by checking the poisoning of the body of consumers around the measurement of bio-markers such as urea, creatinin, transaminase, total cholesterol and urinary calcium of 39 individuals. It has been shown that chronic poisoning to lead via the consumption of drinking water occurred and bio markers witnesses were assessed.
Cotton Culture; Boreholes Water; Blood Lead; Lead Poisoning
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