Paper
Liquid-Liquid Equilibria of Aqueous Two-Phase Systems Containing PEG + Sodium Citrate + Water at various pH
- Authors:
- Vytla Ramachandra Murty; Selvaraj Raja
- Abstract
- Liquid-liquid equilibrium data of aqueous two-phase systems (ATPS) formed by sodium citrate (SC) and poly (ethylene glycol) (PEG) of different molecular weights (600, 1000, 2000, 4000, and 6000) with water was determined at different pH (6, 7, and 8). Binodal data was described using a third order polynomial equation and statistical significance of the parameters was done by regression analysis. The tie-lines were correlated using the Othmer-Tobias and Bancroft equations. An increase in molecular weight of PEG shifted the binodal curve to lower PEG and salt concentrations. An increase in pH showed similar shape and tend to merge at high concentration of PEG and salt.
- Keywords
- Aqueous Two-Phase Systems; Liquid-Liquid Equilibrium; Binodal Curve; Titration Method; Tie-Line Length; Purification; Downstream Processing
- StartPage
- 169
- EndPage
- 174
- Doi