Volume 3 Issue 1

Authors: Otroshy Mahmoud; Moradi Kosar

Abstract: The Dracocephalum Kotschyi L., a wild-growing flowering plant belonging to the family Lamiaceae is best known for the essential oils common to many members of the family. The present study showed the procedure for propagation of D. kotschyi using nodal segments from in vitro germinated plants. A high frequency and rapid regeneration protocol was growing and developing from nodal explants of D. kotschyi on the medium MS containing 2mg/L BAP plus 0.5mg/L NAA. Histochemical analysis showed a direct induction of more teratological protuberances that arise around the cut end of the explants. After hardening, the rooted plants were transferred to the greenhouse condition where they normally grew, matured and flowered with a survival rate of 90-95%. We concluded that the present protocol can be efficiently used for mass propagation of D. kotschyi.

Keywords: Dracocephalum Kotschyi; Explant; Medicinal; Lamiaceae


Authors: Andrey Koptyug; DDS Per Dérand; M.Sc. Sanna Fager Franzén; Mikael Bäckström; Lars-Erik Rännar

Abstract: Present paper is written with the aim to provide an overview of the Additive Manufacturing (AM) technologies in the applications benefiting orthopaedics and prosthetics. To our opinion, modern medicine yet does not fully comprehend existing unique possibilities and emerging opportunities provided by such technologies. Many of the advantages of Additive Manufacturing have been already proven experimentally and are used, but many others tough proven by researchers and method developers are still await to take their rightful place in the arsenal of modern practical medicine. Today the applications of AM technologies are mainly discussed at the specialised forums and in publications targeting the technology specialists. Present paper is written for the existing and potential users of the medical applications of AM technologies. It outlines some of the most interesting achievements of AM technologies along with existing challenges, recent developments and targets for the future.

Keywords: Additive Manufacturing; Implant; Cellular; Patient Specific; Reconstruction; Electron Beam Melting; Composites; Surface


Authors: Murali Raman; Padma Murali

Abstract: Islet Amyloid Polypeptide (IAPP or amylin) is a protein which was first discovered in the year 1987. It is coexpressed and cosecreted in the beta islet cells of the pancreas along with insulin. IAPP forms amyloid plaques in diseased states like type II diabetes mellitus (T2DM) and Hypertension. These comorbidities play an important role in development of cardiovascular diseases(CVD). Thus, control of amyloidosis is vital in prevention and management of T2DM and CVD. In this work, we model the dynamics of amyloid formation of islet beta cells under therapeutic interventions. According to this model the effects of drug therapy on amyloid formation are given by a system of ordinary differential equations and a partial differential equation. The model is then converted into a system of ordinary differential equations and the equilibrium points are computed and their stability is studied. Also, numerical simulations are performed on the model and we conclude that amyloidosis can be controlled in the presence of therapeutic intervention.

Keywords: IAPP; Diabetes Mellitus; Drug Therapy; CVD; Hypertension


Authors: Tokiko Nakagawa; Ikuo Sakaguchi; Lisa Wingenfeld; Satoshi Furukawa; Akari Takaya; Satomu Morita; Katsuji Nishi; Shigeru Yamasaki

Abstract: We examined characteristics or cardiac cell damage in the myocardium obtained from individuals who died due to hypothermia or coldwater immersion. We could find four kinds of histological changes in the heart tissues obtained from hypothermia and coldwater immersion death. Although the red or orange colored cardiac cells, vacuolar cardiac cells and contraction band of the cardiac cells were observed in the heart from individuals with cardiac infarction, the frequency and intensity of the finding was remarkable in hypothermic death, and closely adhered cardiac cells were detected only in the myocardium from hypothermic or coldwater immersion death. We additionally discussed the mechanisms of development of these findings by comparing the results obtained in this examination with some reports in the literatures.

Keywords: Hypothermic Death; Cardiac Cell Damages; Conventional Stain; Diagnosis of Hypothermic Death


Authors: Oleg Grigorovitsh Avrunin; Husham Farouk Ismail Saied

Abstract: Studying aerodynamic processes which happen dur-ing the breathing process in the nasal cavity are an actual problem when trying to diagnose the pathological states of the upper respiratory tract [1-5]. Unobstructed air passageways as well as sufficient contact of the air flow with the mucous mem-brane are essential for the correct function of the nose. For that, local flow phenomena, which often cannot be identified by standard diagnostic methods, are important. We design and validated a method for analytical modeling and numerical simulation of the nasal airflow. The velocity and pressure fields in these reconstructed cavities were calculated for the entire range of physiological nasal inspiration using a mathematical model of pulsating air flow in a smooth tube that reflects the main lows of the respiratory process in the nasal cavity. The model will allow receiving data about the losses of the flow due to the friction effect of the air on the walls of nasal cavity, which indirectly serve to know the state of the mucous mem-brane on the cavity, thus as moisture , friability, etc. In this work the authors adapted the model of pulsating fluid flow rate into a nasal cavity, that allowed by numerically evaluation to calculate the energy dissipation during the air passing through the nasal passage.

Keywords: Nasal Cavity; Nasal Airflow; Axial Speed; Dissipation Function; Pressure Gradient


Authors: Kevin S. Saroka; Blake T. Dotta; Michael A. Persinger

Abstract: In order to replicate and extend the observation that inner light during meditation was associated with specific changes in brain activity, quantitative EEG measurements were completed simultaneously with measurements of photon emissions (with a photomultiplier tube) while three subjects (one concentrative meditator, two non-mediators) imaged an inner white light. There were consistent strong (r=0.5) correlations between photon emission from the right side of the head and changes in power within the right prefrontal-central regions. The quantitative convergence of the energies associated with photon emission, change in cerebral power, and the minute decrease in the local adjacent geomagnetic field in the same plane as the photon emission, suggests that experience of an “inner light” may reflect actual photon production whose energies are shared with changes in the proximal intensity of the geomagnetic field in the plane associated with photon emission.

Keywords: Quantitative EEG; Alpha/Beta Ratios; Meditation; Inner Light; Photon Emission; Geomagnetic Activity; Resonance


Authors: Madziga I.I; A. A. Adesote; Goska D.Y.; Lamidi O.S.; Alawa C.B.I.

Abstract: An experiment was carried out to compare the feedlot assessment of four indigenous breeds of cattle in Nigeria. Ten bulls each of Bunaji, Rahaji, Sokoto Gudali and Azawak weighing between 200-235 kg, with each breed constituting a treatment in a completely randomized design were used for the study. The bulls were fed with sun dried layer litter in a concentrate mixture for 3 months. Significant (P>0.05) differences were observed in total and average daily weight gain and feed: gain ratio between breeds. Water intake was significantly (P>0.05) different across the breeds. Significant (P<0.05) difference was also observed in body condition score of the breeds. Bunaji recorded the highest value while Azawak had the least for body condition score. Rahaji, Sokoto Gudali and Azawak had significantly (P>0.05) better values of feed consumed than Bunaji. Similarly, income over feed cost and feed cost per gain were significantly (P<0.05) different cross the breeds. Rahaji and Sokoto Gudali had higher values for value of gain. It was concluded that fattening Rahaji, Sokoto Gudali and Azawak are more profitable than fattening Bunaji.

Keywords: Feedlot; assessment; indigenous breeds; cattle; Nigeria